Wellness and Research

Cannabinoid Combination Showing Promise for MS Symptoms

Caleb Summeril
Written by Caleb Summeril

The medicinal potential of cannabis is ever expanding. And one condition where common cannabinoids such as THC and CBD have been having a direct impact is with the treatment of some symptoms of the central nervous disease, multiple sclerosis (MS).

A recent pilot study has shown that an oral spray containing both THC and CBD can provide relief for some of the common symptoms associated with MS. [1] This study was conducted by looking at 15 patients with progressive MS and observing how the application of cannabinoids effect spasticity and pain related to the disease. Individuals were tested both before and during the treatment of an oral spray containing THC and CBD and neurophysiological results were observed and then compared to 14 control samples of individuals without the disease of similar age to those affected.

These results were measured using the 9-Hole Peg Test, Modified Ashworth Scale, visual analogue scale, and numeric rating scale. These tests indicated that both spasticity and pain scores for the patients improved across the board as a result of using the cannabinoid infused oral spray. [1] These results are of note as pain relief is an important benefit for anyone afflicted with MS. Improved spasticity also is of importance as MS causes muscles to feel stiff and heavy and these symptoms are relieved with the use of a cannabinoid spray.

The combination of both THC and CBD in this study is also of note as, when taken together, the psychoactive effects of THC can be negated by the presence of CBD. This is important for anyone suffering from MS who wants effective treatment and relief but does not desire the mind-altering effects that can occur with some forms of cannabinoid consumption.

The research is an intriguing application of cannabinoids for a condition that can be difficult to deal with and complex in nature. While the sample size is small, the consistent results it produced are more signs to the potency and practicality of cannabinoids for a treatment in those with MS.

Image source: https://unsplash.com/photos/cRjP2749AL4


  1. Vecchio, Domizia. Et al. Cannabinoids in multiple sclerosis: A neurophysiological analysis. Acta Neurol Scand. 2020 Jul 6.

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Caleb Summeril

Caleb Summeril

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